ASN2/YGR124W Summary Help

Standard Name ASN2 1, 2
Systematic Name YGR124W
Feature Type ORF, Verified
Description Asparagine synthetase; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway; ASN2 has a paralog, ASN1, that arose from the whole genome duplication (2, 3)
Name Description ASparagiNe requiring 1
Chromosomal Location
ChrVII:739944 to 741662 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ASN2 GO evidence and references
  View Computational GO annotations for ASN2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 9 genes
Resources
Pathways
Large-scale survey
null
Resources
36 total interaction(s) for 25 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 14
  • Affinity Capture-RNA: 6
  • Co-purification: 1
  • PCA: 1

Genetic Interactions
  • Negative Genetic: 5
  • Phenotypic Enhancement: 1
  • Positive Genetic: 5
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 572
Molecular Weight (Da) 64,593
Isoelectric Point (pI) 5.73
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:739944 to 741662 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1719 739944..741662 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003356
References cited on this page View Complete Literature Guide for ASN2
1) Jones GE  (1978) L-Asparagine auxotrophs of Saccharomyces cerevisiae: genetic and phenotypic characterization. J Bacteriol 134(1):200-7
2) Dang VD, et al.  (1996) Cloning of the ASN1 and ASN2 genes encoding asparagine synthetases in Saccharomyces cerevisiae: differential regulation by the CCAAT-box-binding factor. Mol Microbiol 22(4):681-92
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61