ASI2/YNL159C Summary Help

Standard Name ASI2 1
Systematic Name YNL159C
Feature Type ORF, Verified
Description Integral inner nuclear membrane protein; acts with Asi1p and Asi3p to ensure the fidelity of SPS-sensor signaling by maintaining the dormant repressed state of gene expression in the absence of inducing signals (1, 2)
Name Description Amino acid Sensor-Independent 1
Chromosomal Location
ChrXIV:339347 to 338478 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ASI2 GO evidence and references
  View Computational GO annotations for ASI2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
12 total interaction(s) for 11 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 2
  • Phenotypic Enhancement: 1
  • Positive Genetic: 1
  • Synthetic Lethality: 1
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 289
Molecular Weight (Da) 32,985
Isoelectric Point (pI) 10.37
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:339347 to 338478 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..870 339347..338478 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005103
References cited on this page View Complete Literature Guide for ASI2
1) Forsberg H, et al.  (2001) Suppressors of ssy1 and ptr3 null mutations define novel amino acid sensor-independent genes in Saccharomyces cerevisiae. Genetics 158(3):973-88
2) Zargari A, et al.  (2007) Inner nuclear membrane proteins asi1, asi2, and asi3 function in concert to maintain the latent properties of transcription factors stp1 and stp2. J Biol Chem 282(1):594-605