ARP6/YLR085C Summary Help

Standard Name ARP6 1
Systematic Name YLR085C
Feature Type ORF, Verified
Description Actin-related protein that binds nucleosomes; a component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A (1, 2)
Name Description Actin-Related Protein 1
Chromosomal Location
ChrXII:301989 to 300673 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ARP6 GO evidence and references
  View Computational GO annotations for ARP6
Molecular Function
Manually curated
Biological Process
Manually curated
High-throughput
Cellular Component
Manually curated
Targets 1781 genes
Regulators 97 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
701 total interaction(s) for 342 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 31
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 5
  • Co-fractionation: 1
  • Co-localization: 1
  • Co-purification: 1

Genetic Interactions
  • Negative Genetic: 343
  • Phenotypic Enhancement: 34
  • Phenotypic Suppression: 19
  • Positive Genetic: 37
  • Synthetic Growth Defect: 133
  • Synthetic Lethality: 88
  • Synthetic Rescue: 7

Resources
Expression Summary
histogram
Resources
Length (a.a.) 438
Molecular Weight (Da) 50,043
Isoelectric Point (pI) 5.31
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:301989 to 300673 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1317 301989..300673 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004075
References cited on this page View Complete Literature Guide for ARP6
1) Poch O and Winsor B  (1997) Who's who among the Saccharomyces cerevisiae actin-related proteins? A classification and nomenclature proposal for a large family. Yeast 13(11):1053-8
2) Wu WH, et al.  (2005) Swc2 is a widely conserved H2AZ-binding module essential for ATP-dependent histone exchange. Nat Struct Mol Biol 12(12):1064-71