Standard Name	ARO9 1, 2
Systematic Name	YHR137W
Feature Type	ORF, Verified
Description	Aromatic aminotransferase II, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism (1, 3)
Name Description	AROmatic amino acid requiring 1

Chromosomal Location	ChrVIII:375709 to 377250 | ORF Map | GBrowse

	View Computational GO annotations for ARO9
Molecular Function
Manually curated	aromatic-amino-acid:2-oxoglutarate aminotransferase activity (IDA, ISS)
Biological Process
Manually curated	aromatic amino acid family metabolic process (IGI, IMP)
Cellular Component
High-throughput	cytoplasm (IDA) nucleus (IDA)

Pathways	methionine salvage pathway pathways of chorismate phenylalanine biosynthesis phenylalanine degradation superpathway of methionine salvage pathway superpathway of phenylalanine, tyrosine and tryptophan biosynthesis tryptophan degradation tyrosine biosynthesis tyrosine degradation

Classical genetics
null	toxin resistance: increased
reduction of function	growth in exponential phase: decreased rate
Large-scale survey
null	competitive fitness: increased Fus-Mid-GFP distribution: abnormal resistance to paromomycin: decreased resistance to cycloheximide: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	20 total interaction(s) for 18 unique genes/features.
Physical Interactions	Affinity Capture-MS: 6 Biochemical Activity: 2 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 1 Phenotypic Enhancement: 1 Positive Genetic: 5 Synthetic Growth Defect: 3 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVIII:375709 to 377250 | ORF Map | GBrowse
	This feature contains embedded feature(s): YHR137C-A
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1542 375709..377250 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001179