ARO9/YHR137W Summary

ARO9 BASIC INFORMATION

Standard Name	ARO9 1, 2
Systematic Name	YHR137W
Feature Type	ORF, Verified
Description	Aromatic aminotransferase II, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism (1, 3)
Name Description	AROmatic amino acid requiring 1

GO Annotations	All ARO9 GO evidence and references
	View Computational GO annotations for ARO9
Molecular Function
Manually curated	aromatic-amino-acid:2-oxoglutarate aminotransferase activity (IDA, ISS)
Biological Process
Manually curated	aromatic amino acid family metabolic process (IGI, IMP)
Cellular Component
High-throughput	cytoplasm (IDA) nucleus (IDA)

Pathways	methionine salvage pathway pathways of chorismate phenylalanine biosynthesis phenylalanine degradation superpathway of methionine salvage pathway superpathway of phenylalanine, tyrosine and tryptophan biosynthesis tryptophan degradation tyrosine biosynthesis tyrosine degradation

Mutant Phenotype	All ARO9 Phenotype details and references
Classical genetics
null	toxin resistance: increased
reduction of function	growth in exponential phase: decreased rate
Large-scale survey
null	viable

Interactions	ARO9 All interactions details and references
	12 total interaction(s) for 12 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Biochemical Activity: 2 Two-hybrid: 1
Genetic Interactions	Phenotypic Enhancement: 1 Synthetic Growth Defect: 3

Sequence Information

ChrVIII:375712 to 377253 | |

This feature contains embedded feature(s): YHR137C-A

Last Update

Coordinates: 2005-11-07 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1542	375712..377253	2005-11-07	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001179

ARO9 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for ARO9

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ARO9]

1)	Iraqui I, et al. (1998) Characterisation of Saccharomyces cerevisiae ARO8 and ARO9 genes encoding aromatic aminotransferases I and II reveals a new aminotransferase subfamily. Mol Gen Genet 257(2):238-48
2)	Fulton, L. (1997) The sequence of S. cerevisiae cosmid 9315. Unpublished
3)	Urrestarazu A, et al. (1998) Phenylalanine- and tyrosine-auxotrophic mutants of Saccharomyces cerevisiae impaired in transamination. Mol Gen Genet 257(2):230-7

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