ARO7/YPR060C Summary Help

Standard Name ARO7 1
Systematic Name YPR060C
Alias HGS1 2 , OSM2 1 , TYR7
Feature Type ORF, Verified
Description Chorismate mutase; catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis (1, 3)
Name Description AROmatic amino acid requiring
Chromosomal Location
ChrXVI:675631 to 674861 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 39.4 cM
Gene Ontology Annotations All ARO7 GO evidence and references
  View Computational GO annotations for ARO7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 3 genes
Resources
Pathways
Classical genetics
activation
null
unspecified
Large-scale survey
null
Resources
148 total interaction(s) for 113 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Co-crystal Structure: 2

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 117
  • Phenotypic Suppression: 1
  • Positive Genetic: 18
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 256
Molecular Weight (Da) 29,747
Isoelectric Point (pI) 6.21
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:675631 to 674861 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: 39.4 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..771 675631..674861 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006264
References cited on this page View Complete Literature Guide for ARO7
1) Ball SG, et al.  (1986) Molecular cloning and characterization of ARO7-OSM2, a single yeast gene necessary for chorismate mutase activity and growth in hypertonic medium. Mol Gen Genet 205(2):326-30
2) Ono B and Sakamoto E  (1985) Saccharomyces cerevisiae strains sensitive to inorganic mercury. I. Effect of tyrosine. Curr Genet 10(3):179-85
3) Jones EW and Fink GR  (1982) "Regulation of amino acid and nucleotide biosynthesis in yeast." Pp.181-299 in The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, edited by Strathern JN, Jones EW and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press