ARL1/YBR164C Summary

ARL1 BASIC INFORMATION

Standard Name	ARL1
Systematic Name	YBR164C
Alias	DLP2
Feature Type	ORF, Verified
Description	Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; G protein of the Ras superfamily, similar to ADP-ribosylation factor (1, 2, 3)
Name Description	ADP-Ribosylation factor-Like 1

GO Annotations	All ARL1 GO evidence and references
	View Computational GO annotations for ARL1
Molecular Function
Manually curated	GTPase activity (IDA, ISS)
Biological Process
Manually curated	Golgi to plasma membrane protein transport (IMP) protein targeting to vacuole (IMP) vesicle-mediated transport (IGI, IMP)
Cellular Component
Manually curated	Golgi apparatus (IDA) soluble fraction (IDA)

Mutant Phenotype	All ARL1 Phenotype details and references
Classical genetics
null	resistance to Congo Red: decreased
Large-scale survey
null	competitive fitness: decreased hyperosmotic stress resistance: decreased resistance to rapamycin: decreased resistance to wortmannin: normal resistance to hygromycin B: decreased viable

Interactions	ARL1 All interactions details and references
	205 total interaction(s) for 111 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 Affinity Capture-Western: 6 Biochemical Activity: 3 Co-localization: 1 PCA: 1 Reconstituted Complex: 2 Two-hybrid: 5
Genetic Interactions	Dosage Rescue: 12 Phenotypic Enhancement: 101 Phenotypic Suppression: 12 Synthetic Growth Defect: 10 Synthetic Lethality: 50 Synthetic Rescue: 1

Sequence Information

ChrII:568421 to 567870 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-07-16 | Sequence: 1997-01-28

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..552	568421..567870	2004-07-16	1997-01-28

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000368

ARL1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for ARL1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ARL1]

1)	Lee FJ, et al. (1997) Characterization of an ADP-ribosylation factor-like 1 protein in Saccharomyces cerevisiae. J Biol Chem 272(49):30998-1005
2)	Rosenwald AG, et al. (2002) ARL1 and membrane traffic in Saccharomyces cerevisiae. Yeast 19(12):1039-56
3)	Munson AM, et al. (2004) Yeast ARL1 encodes a regulator of K+ influx. J Cell Sci 117(Pt 11):2309-20

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