ARH1/YDR376W Summary Help

Standard Name ARH1 1
Systematic Name YDR376W
Feature Type ORF, Verified
Description Oxidoreductase of the mitochondrial inner membrane; involved in cytoplasmic and mitochondrial iron homeostasis and required for activity of Fe-S cluster-containing enzymes; one of the few mitochondrial proteins essential for viability (1, 2, 3)
Name Description Adrenodoxin Reductase Homolog 1
Chromosomal Location
ChrIV:1226822 to 1228303 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ARH1 GO evidence and references
  View Computational GO annotations for ARH1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
repressible
Large-scale survey
null
overexpression
reduction of function
Resources
5 total interaction(s) for 5 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • Two-hybrid: 2

Genetic Interactions
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 493
Molecular Weight (Da) 56,237
Isoelectric Point (pI) 9.6
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1226822 to 1228303 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1482 1226822..1228303 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002784
References cited on this page View Complete Literature Guide for ARH1
1) Manzella L, et al.  (1998) ARH1 of Saccharomyces cerevisiae: a new essential gene that codes for a protein homologous to the human adrenodoxin reductase. Yeast 14(9):839-46
2) Lacour T, et al.  (1998) Characterization of recombinant adrenodoxin reductase homologue (Arh1p) from yeast. Implication in in vitro cytochrome p45011beta monooxygenase system. J Biol Chem 273(37):23984-92
3) Li J, et al.  (2001) Adrenodoxin reductase homolog (Arh1p) of yeast mitochondria required for iron homeostasis. J Biol Chem 276(2):1503-9