Standard Name	ARG80 1
Systematic Name	YMR042W
Alias	ARGR1 2
Feature Type	ORF, Verified
Description	Transcription factor involved in regulation of arginine-responsive genes; acts with Arg81p and Arg82p (2) Also known as: ARGRI 3
Name Description	ARGinine requiring

Chromosomal Location	ChrXIII:352603 to 353136 | ORF Map | GBrowse
	Genetic position: 36 cM

	View Computational GO annotations for ARG80
Molecular Function
Manually curated	core promoter proximal region sequence-specific DNA binding (IDA, IMP) RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity (IC, ISA)
Biological Process
Manually curated	positive regulation of transcription from RNA polymerase II promoter (IMP) regulation of arginine biosynthetic process (IMP) regulation of arginine catabolic process (IMP)
Cellular Component
Manually curated	nucleus (IDA)

Regulatory modules	predicted: stressResponse (613)
Resources	ScerTF | YEASTRACT | YeTFaSCo

Classical genetics
null	vegetative growth: absent
reduction of function	ornithine transaminase activity: decreased arginase activity: decreased ornithine carbamoyltransferase activity: increased vegetative growth: decreased rate
Large-scale survey
null	competitive fitness: decreased haploinsufficient resistance to L-canavanine: increased resistance to sirolimus: decreased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	36 total interaction(s) for 25 unique genes/features.
Physical Interactions	Affinity Capture-Western: 2 Reconstituted Complex: 1 Two-hybrid: 12
Genetic Interactions	Negative Genetic: 2 Phenotypic Enhancement: 2 Positive Genetic: 15 Synthetic Growth Defect: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:352603 to 353136 | ORF Map | GBrowse
	Genetic position: 36 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..534 352603..353136 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004645