ARE1/YCR048W Summary Help

ARE1 BASIC INFORMATION

Standard Name ARE1 1
Systematic Name YCR048W
Alias SAT2 2
Feature Type ORF, Verified
Description Acyl-CoA:sterol acyltransferase, isozyme of Are2p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the absence of oxygen (2, 3, 4)
Name Description Acyl-coenzyme A: cholesterol acyl transferase-Related Enzyme 1
GO Annotations All ARE1 GO evidence and references
    View Computational GO annotations for ARE1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All ARE1 Phenotype details and references
Large-scale survey
null
Interactions ARE1 All interactions details and references
22 total interaction(s) for 11 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Two-hybrid: 2
Genetic Interactions
  • Phenotypic Enhancement: 16
  • Phenotypic Suppression: 2
  • Synthetic Lethality: 1
Sequence Information
ChrIII:211925 to 213757 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2006-01-12 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1833 211925..213757 2006-01-12 1997-01-28
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000644

ARE1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for ARE1

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
AGE2Nomenclature conflictSAT2 has been used in the literature to refer to both ARE1/YCR048W, which encodes a sterol O-acyltransferase, and AGE2/YIL044C, which encodes an ARF GTPase activator.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ARE1]

1) Yang H, et al.  (1996) Sterol esterification in yeast: a two-gene process. Science 272(5266):1353-6
2) Yu C, et al.  (1996) Molecular cloning and characterization of two isoforms of Saccharomyces cerevisiae acyl-CoA:sterol acyltransferase. J Biol Chem 271(39):24157-63
3) Zweytick D, et al.  (2000) Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae. Eur J Biochem 267(4):1075-82
4) Valachovic M, et al.  (2001) Anaerobiosis induces complex changes in sterol esterification pattern in the yeast Saccharomyces cerevisiae. FEMS Microbiol Lett 197(1):41-5