AQY2/YLL052C Summary Help

Standard Name AQY2 1
Systematic Name YLL052C
Feature Type ORF, Verified
Description Water channel that mediates water transport across cell membranes; only expressed in proliferating cells; controlled by osmotic signals; may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains (2, 3, 4)
Name Description AQuaporin of Yeast 1, 5
Chromosomal Location
ChrXII:36361 to 35912 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All AQY2 GO evidence and references
  View Computational GO annotations for AQY2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 8 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
17 total interaction(s) for 10 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 7
  • Positive Genetic: 7
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 149
Molecular Weight (Da) 17,024
Isoelectric Point (pI) 4.75
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:36361 to 35912 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..450 36361..35912 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000003975
References cited on this page View Complete Literature Guide for AQY2
1) Laize V, et al.  (2000) Polymorphism of Saccharomyces cerevisiae aquaporins. Yeast 16(10):897-903
2) Carbrey JM, et al.  (2001) Aquaporins in Saccharomyces: Characterization of a second functional water channel protein. Proc Natl Acad Sci U S A 98(3):1000-5
3) Tanghe A, et al.  (2002) Aquaporin expression correlates with freeze tolerance in baker's yeast, and overexpression improves freeze tolerance in industrial strains. Appl Environ Microbiol 68(12):5981-9
4) Pettersson N, et al.  (2005) Aquaporins in yeasts and filamentous fungi. Biol Cell 97(7):487-500
5) Bonhivers M, et al.  (1998) Aquaporins in Saccharomyces. Genetic and functional distinctions between laboratory and wild-type strains. J Biol Chem 273(42):27565-72