APT2/YDR441C Summary Help

APT2 BASIC INFORMATION

Standard Name APT2
Systematic Name YDR441C
Feature Type ORF, Verified
Description Apparent pseudogene, not transcribed or translated under normal conditions; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity (1 and see Summary Paragraph)
Name Description Adenine PhosphoribosylTransferase
GO Annotations All APT2 GO evidence and references
    View Computational GO annotations for APT2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Pathways
Mutant Phenotype All APT2 Phenotype details and references
Large-scale survey
null
Interactions APT2 All interactions details and references
9 total interaction(s) for 7 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Protein-RNA: 1
  • Two-hybrid: 1
Genetic Interactions
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 5
Sequence Information
ChrIV:1345055 to 1344510 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2008-06-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..546 1345055..1344510 2008-06-05 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002849

APT2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for APT2

SUMMARY PARAGRAPH for APT2

APT2 is a gene with similarity to adenine phosphoribosyltransferase (APRT) (2). It is likely a pseudogene that arose via duplication of the APRT-encoding gene APT1 (). APT2 expressed in E. coli shows no APRT activity, and the gene is not expressed under normal physiological conditions in yeast (1).

Last updated: 1999-12-31

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for APT2]

1) Alfonzo JD, et al.  (1999) APT1, but not APT2, codes for a functional adenine phosphoribosyltransferase in Saccharomyces cerevisiae. J Bacteriol 181(1):347-52
2) Yuryev A and Corden JL  (1994) A Saccharomyces cerevisiae gene encoding a potential adenine phosphoribosyltransferase. Yeast 10(5):659-62