APS2/YJR058C Summary Help

APS2 BASIC INFORMATION

Standard Name APS2
Systematic Name YJR058C
Alias YAP17 1
Feature Type ORF, Verified
Description Small subunit of the clathrin-associated adaptor complex AP-2, which is involved in protein sorting at the plasma membrane; related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex (1, 2, 3)
Name Description clathrin Associated Protein complex Small subunit
GO Annotations All APS2 GO evidence and references
    View Computational GO annotations for APS2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All APS2 Phenotype details and references
Large-scale survey
null
Interactions APS2 All interactions details and references
11 total interaction(s) for 7 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • Biochemical Activity: 1
  • Two-hybrid: 2
Genetic Interactions
  • Synthetic Growth Defect: 1
Sequence Information
ChrX:545167 to 544724 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2009-02-18 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..444 545167..544724 2009-02-18 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003819

APS2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for APS2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for APS2]

1) Kirchhausen T, et al.  (1991) AP17 and AP19, the mammalian small chains of the clathrin-associated protein complexes show homology to Yap17p, their putative homolog in yeast. J Biol Chem 266(17):11153-7
2) Phan HL, et al.  (1994) The Saccharomyces cerevisiae APS1 gene encodes a homolog of the small subunit of the mammalian clathrin AP-1 complex: evidence for functional interaction with clathrin at the Golgi complex. EMBO J 13(7):1706-17
3) Cowles CR, et al.  (1997) The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole. Cell 91(1):109-18