APS1/YLR170C Summary Help

APS1 BASIC INFORMATION

Standard Name APS1 1
Systematic Name YLR170C
Alias YAP19 2
Feature Type ORF, Verified
Description Small subunit of the clathrin-associated adaptor complex AP-1, which is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex (1, 2, 3)
Name Description clathrin Associated Protein complex Small subunit 1
GO Annotations All APS1 GO evidence and references
    View Computational GO annotations for APS1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All APS1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions APS1 All interactions details and references
35 total interaction(s) for 15 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 22
  • Affinity Capture-Western: 7
  • PCA: 1
  • Two-hybrid: 2
Genetic Interactions
  • Synthetic Growth Defect: 2
  • Synthetic Rescue: 1
Sequence Information
ChrXII:501051 to 500581 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..471 501051..500581 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004160

APS1 RESOURCES

Click on map for expanded view
SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for APS1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for APS1]

1) Phan HL, et al.  (1994) The Saccharomyces cerevisiae APS1 gene encodes a homolog of the small subunit of the mammalian clathrin AP-1 complex: evidence for functional interaction with clathrin at the Golgi complex. EMBO J 13(7):1706-17
2) Nakai M, et al.  (1993) Cloning of the YAP19 gene encoding a putative yeast homolog of AP19, the mammalian small chain of the clathrin-assembly proteins. Biochim Biophys Acta 1174(3):282-4
3) Cowles CR, et al.  (1997) The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole. Cell 91(1):109-18