APM3/YBR288C Summary Help

Standard Name APM3
Systematic Name YBR288C
Alias YKS6 1
Feature Type ORF, Verified
Description Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway (2, 3, 4)
Name Description clathrin Adaptor Protein complex Medium chain
Chromosomal Location
ChrII:779463 to 778012 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All APM3 GO evidence and references
  View Computational GO annotations for APM3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
193 total interaction(s) for 113 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 22
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • PCA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 124
  • Phenotypic Enhancement: 2
  • Positive Genetic: 26
  • Synthetic Growth Defect: 5
  • Synthetic Lethality: 7
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 483
Molecular Weight (Da) 54,837
Isoelectric Point (pI) 6.52
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:779463 to 778012 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1452 779463..778012 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000492
References cited on this page View Complete Literature Guide for APM3
1) Panek HR, et al.  (1997) Suppressors of YCK-encoded yeast casein kinase 1 deficiency define the four subunits of a novel clathrin AP-like complex. EMBO J 16(14):4194-204
2) Cowles CR, et al.  (1997) The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole. Cell 91(1):109-18
3) Yeung BG, et al.  (1999) Adaptor complex-independent clathrin function in yeast. Mol Biol Cell 10(11):3643-59
4) Odorizzi G, et al.  (1998) The AP-3 complex: a coat of many colours. Trends Cell Biol 8(7):282-8