APL5/YPL195W Summary Help

APL5 BASIC INFORMATION

Standard Name APL5 1
Systematic Name YPL195W
Alias YKS4 2
Feature Type ORF, Verified
Description Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function (1, 2, 3)
Name Description clathrin Adaptor Protein complex Large chain 1
GO Annotations All APL5 GO evidence and references
    View Computational GO annotations for APL5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All APL5 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions APL5 All interactions details and references
127 total interaction(s) for 64 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 17
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 4
  • Co-purification: 1
  • PCA: 1
  • Reconstituted Complex: 11
  • Two-hybrid: 2
Genetic Interactions
  • Phenotypic Enhancement: 76
  • Phenotypic Suppression: 8
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 3
  • Synthetic Rescue: 2
Sequence Information
ChrXVI:176222 to 179020 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2799 176222..179020 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000006116

APL5 RESOURCES

Click on map for expanded view
SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for APL5

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for APL5]

1) Cowles CR, et al.  (1997) The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole. Cell 91(1):109-18
2) Panek HR, et al.  (1997) Suppressors of YCK-encoded yeast casein kinase 1 deficiency define the four subunits of a novel clathrin AP-like complex. EMBO J 16(14):4194-204
3) Rehling P, et al.  (1999) Formation of AP-3 transport intermediates requires Vps41 function. Nat Cell Biol 1(6):346-53