APL3/YBL037W Summary Help

Standard Name APL3
Systematic Name YBL037W
Feature Type ORF, Verified
Description Alpha-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport (1, 2, 3)
Name Description clathrin Adaptor Protein complex Large chain
Chromosomal Location
ChrII:147209 to 150286 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All APL3 GO evidence and references
  View Computational GO annotations for APL3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Large-scale survey
null
Resources
50 total interaction(s) for 41 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 18
  • Affinity Capture-RNA: 3
  • Biochemical Activity: 1
  • Protein-RNA: 1
  • Two-hybrid: 11

Genetic Interactions
  • Negative Genetic: 14
  • Positive Genetic: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,025
Molecular Weight (Da) 115,010
Isoelectric Point (pI) 8.97
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:147209 to 150286 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3078 147209..150286 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000133
References cited on this page View Complete Literature Guide for APL3
1) Panek HR, et al.  (1997) Suppressors of YCK-encoded yeast casein kinase 1 deficiency define the four subunits of a novel clathrin AP-like complex. EMBO J 16(14):4194-204
2) Kirchhausen T  (2000) Three ways to make a vesicle. Nat Rev Mol Cell Biol 1(3):187-98
3) Yeung BG, et al.  (1999) Adaptor complex-independent clathrin function in yeast. Mol Biol Cell 10(11):3643-59