Standard Name	APE3
Systematic Name	YBR286W
Alias	APY1
Feature Type	ORF, Verified
Description	Vacuolar aminopeptidase Y, processed to mature form by Prb1p (1, 2)
Name Description	AminoPEptidase

Chromosomal Location	ChrII:774700 to 776313 | ORF Map | GBrowse

	View Computational GO annotations for APE3
Molecular Function
Manually curated	aminopeptidase activity (IDA, IMP)
Biological Process
Manually curated	vacuolar protein catabolic process (IDA)
Cellular Component
Manually curated	fungal-type vacuole (IDA)

Large-scale survey
null	acid pH resistance: decreased competitive fitness: decreased haploinsufficient heat sensitivity: increased resistance to sodium selenide: decreased resistance to arsenite(3-): decreased telomere length: decreased toxin resistance: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	24 total interaction(s) for 22 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 4
Genetic Interactions	Negative Genetic: 5 Phenotypic Enhancement: 2 Positive Genetic: 4 Synthetic Growth Defect: 3 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:774700 to 776313 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 2005-11-07
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1614 774700..776313 2011-02-03 2005-11-07
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000490