ANP1/YEL036C Summary Help

Standard Name ANP1 1
Systematic Name YEL036C
Alias GEM3 , MNN8
Feature Type ORF, Verified
Description Subunit of the alpha-1,6 mannosyltransferase complex; type II membrane protein; has a role in retention of glycosyltransferases in the Golgi; involved in osmotic sensitivity and resistance to aminonitrophenyl propanediol (1, 2)
Name Description ANP and osmotic sensitive 1
Chromosomal Location
ChrV:84552 to 83050 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: -26 cM
Gene Ontology Annotations All ANP1 GO evidence and references
  View Computational GO annotations for ANP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
null
unspecified
Large-scale survey
null
overexpression
Resources
557 total interaction(s) for 509 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 28
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 16
  • Co-fractionation: 6
  • Co-purification: 1
  • PCA: 1

Genetic Interactions
  • Dosage Lethality: 3
  • Dosage Rescue: 1
  • Negative Genetic: 371
  • Positive Genetic: 119
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 6

Resources
Expression Summary
histogram
Resources
Length (a.a.) 500
Molecular Weight (Da) 58,182
Isoelectric Point (pI) 5.04
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:84552 to 83050 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: -26 cM
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1503 84552..83050 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000762
References cited on this page View Complete Literature Guide for ANP1
1) Melnick L and Sherman F  (1993) The gene clusters ARC and COR on chromosomes 5 and 10, respectively, of Saccharomyces cerevisiae share a common ancestry. J Mol Biol 233(3):372-88
2) Jungmann J, et al.  (1999) The Saccharomyces cerevisiae protein Mnn10p/Bed1p is a subunit of a Golgi mannosyltransferase complex. J Biol Chem 274(10):6579-85