AMS1 BASIC INFORMATION
| Standard Name | AMS1 1 |
|---|---|
| Systematic Name | YGL156W |
| Feature Type | ORF, Verified |
| Description | Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway (2, 3, 4)
|
| Name Description | Alpha-MannoSidase 1 |
| GO Annotations | All AMS1 GO evidence and references |
|---|---|
| View Computational GO annotations for AMS1 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated |
| Mutant Phenotype | All AMS1 Phenotype details and references |
|---|---|
| Classical genetics | |
| unspecified | |
| Large-scale survey | |
| null |
| Interactions | AMS1 All interactions details and references |
|---|---|
| 9 total interaction(s) for 6 unique genes/features. | |
| Physical Interactions |
|
| External Links | All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB |
|---|
| Primary SGDID | S000003124 |
|---|
ADDITIONAL INFORMATION for AMS1
REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for AMS1]
| 1) | Yoshihisa T and Anraku Y (1989) Nucleotide sequence of AMS1, the structure gene of vacuolar alpha-mannosidase of Saccharomyces cerevisiae. Biochem Biophys Res Commun 163(2):908-15 |
| 2) | Yoshihisa T and Anraku Y (1990) A novel pathway of import of alpha-mannosidase, a marker enzyme of vacuolar membrane, in Saccharomyces cerevisiae. J Biol Chem 265(36):22418-25 |
| 3) | Hutchins MU and Klionsky DJ (2001) Vacuolar localization of oligomeric alpha-mannosidase requires the cytoplasm to vacuole targeting and autophagy pathway components in Saccharomyces cerevisiae. J Biol Chem 276(23):20491-8 |
| 4) | Chantret I, et al. (2003) Free-oligosaccharide control in the yeast Saccharomyces cerevisiae: roles for peptide:N-glycanase (Png1p) and vacuolar mannosidase (Ams1p). Biochem J 373(Pt 3):901-8 |




