AMS1/YGL156W Summary Help

AMS1 BASIC INFORMATION

Standard Name AMS1 1
Systematic Name YGL156W
Feature Type ORF, Verified
Description Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway (2, 3, 4)
Name Description Alpha-MannoSidase 1
GO Annotations All AMS1 GO evidence and references
    View Computational GO annotations for AMS1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All AMS1 Phenotype details and references
Classical genetics
unspecified
Large-scale survey
null
Interactions AMS1 All interactions details and references
9 total interaction(s) for 6 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-Western: 1
  • Co-fractionation: 1
  • Two-hybrid: 3

Sequence Information
ChrVII:210421 to 213672 | ORF Map | GBrowse
Gbrowse
Genetic position: -98 cM
Last Update Coordinates: 2004-07-20 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3252 210421..213672 2004-07-20 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003124

AMS1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for AMS1]

1) Yoshihisa T and Anraku Y  (1989) Nucleotide sequence of AMS1, the structure gene of vacuolar alpha-mannosidase of Saccharomyces cerevisiae. Biochem Biophys Res Commun 163(2):908-15
2) Yoshihisa T and Anraku Y  (1990) A novel pathway of import of alpha-mannosidase, a marker enzyme of vacuolar membrane, in Saccharomyces cerevisiae. J Biol Chem 265(36):22418-25
3) Hutchins MU and Klionsky DJ  (2001) Vacuolar localization of oligomeric alpha-mannosidase requires the cytoplasm to vacuole targeting and autophagy pathway components in Saccharomyces cerevisiae. J Biol Chem 276(23):20491-8
4) Chantret I, et al.  (2003) Free-oligosaccharide control in the yeast Saccharomyces cerevisiae: roles for peptide:N-glycanase (Png1p) and vacuolar mannosidase (Ams1p). Biochem J 373(Pt 3):901-8