| Standard Name | ALT2 1, 2 |
|---|---|
| Systematic Name | YDR111C |
| Feature Type | ORF, Uncharacterized |
| Description | Catalytically inactive alanine transaminase; expression is repressed in the presence of alanine and repression is mediated by Nrg1p; ALT2 has a paralog, ALT1, that arose from the whole genome duplication (2, 3, 4) |
| Name Description | ALanine Transaminase 2 |
| Chromosomal Location | |
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| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All ALT2 GO evidence and references
| View Computational GO annotations for ALT2 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated |
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| Cellular Component | |
| High-throughput |
Mutant phenotypes All ALT2 Phenotype evidence and references
| Large-scale survey | |
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| null |
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| overexpression | |
| Resources |
interactions All ALT2 Interaction evidence and references
| 34 total interaction(s) for 29 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All ALT2 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000002518 |
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References cited on this page View Complete Literature Guide for ALT2
| 1) | Anaya V, et al. (2003) personal communication |
| 2) | Blank LM, et al. (2005) Metabolic-flux and network analysis in fourteen hemiascomycetous yeasts. FEMS Yeast Res 5(6-7):545-58 |
| 3) | Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 |
| 4) | Penalosa-Ruiz G, et al. (2012) Paralogous ALT1 and ALT2 Retention and Diversification Have Generated Catalytically Active and Inactive Aminotransferases in Saccharomyces cerevisiae. PLoS One 7(9):e45702 |




