ALR1/YOL130W Summary Help

ALR1 BASIC INFORMATION

Standard Name ALR1 1
Systematic Name YOL130W
Alias SWC3
Feature Type ORF, Verified
Description Plasma membrane Mg(2+) transporter, expression and turnover are regulated by Mg(2+) concentration; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions (1, 2, 3)
Name Description ALuminum Resistance 1
GO Annotations All ALR1 GO evidence and references
    View Computational GO annotations for ALR1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All ALR1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
overexpression
Interactions ALR1 All interactions details and references
21 total interaction(s) for 18 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 6
  • Two-hybrid: 8
Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 2
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 1
Sequence Information
ChrXV:74400 to 76979 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2580 74400..76979 2006-01-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | TCDB | UniProtKB
Primary SGDIDS000005490

ALR1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for ALR1

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
SWC3Nomenclature conflictSWC3 has been used to refer to both SWC3/YAL011W, whose gene product is involved in chromatin remodeling and ER biogenesis, and ALR1/YOL130W, a plasma membrane transporter.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ALR1]

1) MacDiarmid CW and Gardner RC  (1998) Overexpression of the Saccharomyces cerevisiae magnesium transport system confers resistance to aluminum ion. J Biol Chem 273(3):1727-32
2) Graschopf A, et al.  (2001) The yeast plasma membrane protein Alr1 controls Mg2+ homeostasis and is subject to Mg2+-dependent control of its synthesis and degradation. J Biol Chem 276(19):16216-22
3) Liu GJ, et al.  (2002) Large Mg(2+)-dependent currents are associated with the increased expression of ALR1 in Saccharomyces cerevisiae. FEMS Microbiol Lett 213(2):231-7