AIM4/YBR194W Summary Help

Standard Name AIM4 1
Systematic Name YBR194W
Alias SOY1 2 , 3
Feature Type ORF, Verified
Description Protein proposed to be associated with the nuclear pore complex; null mutant is viable, displays elevated frequency of mitochondrial genome loss and is sensitive to freeze-thaw stress (1, 4, 5)
Name Description Altered Inheritance rate of Mitochondria 1
Chromosomal Location
ChrII:610038 to 610409 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All AIM4 GO evidence and references
  View Computational GO annotations for AIM4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
309 total interaction(s) for 286 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 157
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • Co-purification: 1
  • Two-hybrid: 3

Genetic Interactions
  • Negative Genetic: 116
  • Positive Genetic: 11
  • Synthetic Growth Defect: 13
  • Synthetic Lethality: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 123
Molecular Weight (Da) 14,234
Isoelectric Point (pI) 11
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:610038 to 610409 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..372 610038..610409 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000398
References cited on this page View Complete Literature Guide for AIM4
1) Hess DC, et al.  (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407
2) Amberg, D.  (2003) personal communication
3) Ando A, et al.  (2007) Identification and classification of genes required for tolerance to freeze-thaw stress revealed by genome-wide screening of Saccharomyces cerevisiae deletion strains. FEMS Yeast Res 7(2):244-53
4) Rout MP, et al.  (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51
5) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91