AIM21/YIR003W Summary Help

Standard Name AIM21 1
Systematic Name YIR003W
Feature Type ORF, Verified
Description Protein of unknown function; involved in mitochondrial migration along actin filament; may interact with ribosomes; GFP-fusion protein colocalizes with Sac1p to the actin cytoskeleton (1, 2, 3, 4, 5, 6)
Name Description Altered Inheritance rate of Mitochondria 1
Chromosomal Location
ChrIX:360885 to 362924 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All AIM21 GO evidence and references
  View Computational GO annotations for AIM21
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 9 genes
Resources
Large-scale survey
null
Resources
50 total interaction(s) for 35 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 13
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 6
  • PCA: 2
  • Protein-peptide: 2
  • Two-hybrid: 3

Genetic Interactions
  • Negative Genetic: 16
  • Positive Genetic: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 679
Molecular Weight (Da) 74,762
Isoelectric Point (pI) 4.74
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:360885 to 362924 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2040 360885..362924 2011-02-03 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001442
References cited on this page View Complete Literature Guide for AIM21
1) Hess DC, et al.  (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407
2) Fazi B, et al.  (2002) Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis. J Biol Chem 277(7):5290-8
3) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
4) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
5) Landgraf C, et al.  (2004) Protein interaction networks by proteome peptide scanning. PLoS Biol 2(1):E14
6) Fleischer TC, et al.  (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307