Standard Name	AGP2 1
Systematic Name	YBR132C
Feature Type	ORF, Verified
Description	High affinity polyamine permease, preferentially uses spermidine over putrescine; expression is down-regulated by osmotic stress; plasma membrane carnitine transporter, also functions as a low-affinity amino acid permease (1, 2, 3, 4)
Name Description	high-Affinity Glutamine Permease 1

Chromosomal Location	ChrII:501442 to 499652 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for AGP2
Molecular Function
Manually curated	amino acid transmembrane transporter activity (IMP) carnitine transmembrane transporter activity (IDA) polyamine transmembrane transporter activity (IMP)
Biological Process
Manually curated	amino acid transport (IMP) carnitine transport (IDA) fatty acid metabolic process (IDA) polyamine transport (IMP) response to osmotic stress (IDA) transmembrane transport (IDA)
Cellular Component
Manually curated	endoplasmic reticulum membrane (IDA) fungal-type vacuole membrane (IDA) integral to plasma membrane (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
null	metal resistance: decreased resistance to Bleomycin-A5: increased resistance to spermine: increased resistance to spermidine: increased resistance to hygromycin B: increased resistance to 1-O-hexadecyl-2-acetyl-sn-glycerophosphocholine: decreased resistance to 1-O-hexadecyl-sn-glycerophosphocholine: decreased
Large-scale survey
null	acid pH resistance: decreased alkaline pH resistance: decreased cell size: decreased competitive fitness: decreased haploinsufficient metal resistance: decreased resistance to nickel(2+): increased resistance to sulfometuron methyl: decreased resistance to tunicamycin: decreased resistance to ethanol: decreased telomere length: decreased transposable element transposition: increased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	22 total interaction(s) for 21 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 PCA: 3 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 16
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:501442 to 499652 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1791 501442..499652 2011-02-03 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB

Primary SGDID	S000000336