Standard Name	AGE2 (see Nomenclature conflict Note)
Systematic Name	YIL044C
Alias	SAT2
Feature Type	ORF, Verified
Description	ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in Trans-Golgi-Network (TGN) transport; contains C2C2H2 cysteine/histidine motif (1, 2, 3)
Name Description	Arf Gap with Effector function(s)

Chromosomal Location	ChrIX:273846 to 272950 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for AGE2
Molecular Function
Manually curated	ARF GTPase activator activity (IDA, IGI, ISS)
Biological Process
Manually curated	ER to Golgi vesicle-mediated transport (IGI, ISS) intra-Golgi vesicle-mediated transport (IGI, ISS)
Cellular Component
High-throughput	colocalizes_with clathrin-coated vesicle (IDA)

Large-scale survey
null	auxotrophy inositol excretion: increased competitive fitness: decreased hyperosmotic stress resistance: decreased resistance to bleomycin: decreased resistance to caffeine: decreased resistance to fenpropimorph: decreased resistance to fluconazole: decreased resistance to mycophenolic acid: decreased resistance to cycloheximide: decreased resistance to benzo[a]pyrene: decreased stress resistance: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	127 total interaction(s) for 79 unique genes/features.
Physical Interactions	Biochemical Activity: 2 PCA: 1
Genetic Interactions	Dosage Rescue: 4 Negative Genetic: 95 Phenotypic Enhancement: 1 Positive Genetic: 11 Synthetic Growth Defect: 8 Synthetic Lethality: 3 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIX:273846 to 272950 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..897 273846..272950 2011-02-03 1994-12-10
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001306