AGA1/YNR044W Summary Help

Standard Name AGA1
Systematic Name YNR044W
Feature Type ORF, Verified
Description Anchorage subunit of a-agglutinin of a-cells; highly O-glycosylated protein with N-terminal secretion signal and C-terminal signal for addition of GPI anchor to cell wall, linked to adhesion subunit Aga2p via two disulfide bonds; AGA1 has a paralog, FIG2, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description a cell-specific sexual AGglutination
Gene Product Alias a-agglutinin anchorage subunit 1
Chromosomal Location
ChrXIV:703699 to 705876 | ORF Map | GBrowse
Gbrowse
Genetic position: 42 cM
Gene Ontology Annotations All AGA1 GO evidence and references
  View Computational GO annotations for AGA1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 20 genes
Resources
Classical genetics
null
unspecified
Large-scale survey
null
Resources
28 total interaction(s) for 25 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1
  • Protein-RNA: 1

Genetic Interactions
  • Negative Genetic: 17
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 1
  • Synthetic Lethality: 3
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 725
Molecular Weight (Da) 73,353
Isoelectric Point (pI) 4.5
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:703699 to 705876 | ORF Map | GBrowse
SGD ORF map
Genetic position: 42 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2178 703699..705876 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005327
References cited on this page View Complete Literature Guide for AGA1
1) Roy A, et al.  (1991) The AGA1 product is involved in cell surface attachment of the Saccharomyces cerevisiae cell adhesion glycoprotein a-agglutinin. Mol Cell Biol 11(8):4196-206
2) de Nobel H, et al.  (1995) Genetics of a-agglutunin function in Saccharomyces cerevisiae. Mol Gen Genet 247(4):409-15
3) Zhao H, et al.  (2001) Interaction of alpha-agglutinin and a-agglutinin, Saccharomyces cerevisiae sexual cell adhesion molecules. J Bacteriol 183(9):2874-80
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61