Standard Name	ADO1 1
Systematic Name	YJR105W
Feature Type	ORF, Verified
Description	Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle (1)
Name Description	ADenOsine kinase 1

Chromosomal Location	ChrX:623581 to 624603 | ORF Map | GBrowse

	View Computational GO annotations for ADO1
Molecular Function
Manually curated	adenosine kinase activity (IDA, IMP)
Biological Process
Manually curated	purine nucleobase metabolic process (IMP)
Cellular Component
High-throughput	cytoplasm (IDA) nucleus (IDA)

Pathways	salvage pathways of adenine, hypoxanthine, and their nucleosides salvage pathways of purines and their nucleosides superpathway of purine biosynthesis and salvage pathways

Classical genetics
null	glycogen accumulation: increased resistance to cordycepin: increased
Large-scale survey
null	proton accumulation: decreased glycogen accumulation: increased competitive fitness: decreased dessication resistance: decreased fermentative growth: decreased rate heat sensitivity: increased Fus-Mid-GFP distribution: abnormal resistance to amitrole: decreased resistance to cycloheximide: decreased resistance to hydroxyurea: increased resistance to oleate: decreased resistance to dihydromotuporamine C: decreased resistance to ethanol: decreased resistance to tunicamycin: decreased resistance to hygromycin B: decreased resistance to L-1,4-dithiothreitol: decreased telomere length: decreased toxin resistance: increased utilization of phosphorus source: decreased vegetative growth: decreased rate viable
overexpression	filamentous growth: increased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	173 total interaction(s) for 165 unique genes/features.
Physical Interactions	Affinity Capture-MS: 14 Biochemical Activity: 4 PCA: 2 Reconstituted Complex: 1
Genetic Interactions	Negative Genetic: 78 Positive Genetic: 60 Synthetic Growth Defect: 3 Synthetic Lethality: 6 Synthetic Rescue: 5
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrX:623581 to 624603 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1023 623581..624603 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003866