ACA1/YER045C Summary Help

Standard Name ACA1 1
Systematic Name YER045C
Feature Type ORF, Verified
Description ATF/CREB family basic leucine zipper (bZIP) transcription factor; binds as a homodimer to the ATF/CREB consensus sequence TGACGTCA; important for carbon source utilization; target genes include GRE2 and COS8; ACA1 has a paralog, CST6, that arose from the whole genome duplication (1, 2, 3)
Name Description ATF/CREB Activator 1
Chromosomal Location
ChrV:241501 to 240032 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ACA1 GO evidence and references
  View Computational GO annotations for ACA1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Targets 4 genes
Regulators 8 genes
Resources
Large-scale survey
null
overexpression
Resources
37 total interaction(s) for 36 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3
  • Two-hybrid: 12

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 19
  • Positive Genetic: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 489
Molecular Weight (Da) 54,592
Isoelectric Point (pI) 8.09
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:241501 to 240032 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1470 241501..240032 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000847
References cited on this page View Complete Literature Guide for ACA1
1) Garcia-Gimeno MA and Struhl K  (2000) Aca1 and Aca2, ATF/CREB activators in Saccharomyces cerevisiae, are important for carbon source utilization but not the response to stress. Mol Cell Biol 20(12):4340-9
2) Spode I, et al.  (2002) ATF/CREB sites present in sub-telomeric regions of Saccharomyces cerevisiae chromosomes are part of promoters and act as UAS/URS of highly conserved COS genes. J Mol Biol 319(2):407-20
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61