ABZ2/YMR289W Summary

ABZ2 BASIC INFORMATION

Standard Name	ABZ2 1
Systematic Name	YMR289W
Feature Type	ORF, Verified
Description	Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase), catalyzes the third step in para-aminobenzoic acid biosynthesis; involved in folic acid biosynthesis (1)
Name Description	para-AminoBenZoic acid (PABA) biosynthesis 1

GO Annotations	All ABZ2 GO evidence and references
	View Computational GO annotations for ABZ2
Molecular Function
Manually curated	4-amino-4-deoxychorismate lyase activity (IDA)
Biological Process
Manually curated	folic acid biosynthetic process (IMP)
Cellular Component
High-throughput	cytoplasm (IDA)

Pathways	folate biosynthesis

Mutant Phenotype	All ABZ2 Phenotype details and references
Large-scale survey
null	auxotrophy competitive fitness: decreased resistance to sulfanilamide: decreased toxin resistance: decreased viable

Interactions	ABZ2 All interactions details and references
	3 total interaction(s) for 3 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Reconstituted Complex: 1 Two-hybrid: 1

Sequence Information

ChrXIII:848684 to 849808 | |

Last Update

Coordinates: 2004-02-27 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1125	848684..849808	2004-02-27	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004902

ABZ2 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for ABZ2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ABZ2]

1)	Botet J, et al. (2007) A Chemogenomic Screening of Sulfanilamide-Hypersensitive Saccharomyces cerevisiae Mutants Uncovers ABZ2, the Gene Encoding a Fungal Aminodeoxychorismate Lyase. Eukaryot Cell 6(11):2102-11

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