AAT1/YKL106W Summary

AAT1 BASIC INFORMATION

Standard Name	AAT1
Systematic Name	YKL106W
Feature Type	ORF, Verified
Description	Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis (1)
Name Description	Aspartate AminoTransferase 1

GO Annotations	All AAT1 GO evidence and references
	View Computational GO annotations for AAT1
Molecular Function
Manually curated	L-aspartate:2-oxoglutarate aminotransferase activity (ISS)
Biological Process
Manually curated	asparagine biosynthetic process from oxaloacetate (IC) aspartate biosynthetic process (IC) aspartate catabolic process (TAS) chronological cell aging (IMP) replicative cell aging (IMP)
Cellular Component
Manually curated	mitochondrion (TAS)
High-throughput	mitochondrion (IDA)

Pathways	asparagine biosynthesis asparagine degradation aspartate biosynthesis superpathway of threonine biosynthesis

Mutant Phenotype	All AAT1 Phenotype details and references
Classical genetics
null	replicative lifespan: decreased
overexpression	chronological lifespan: increased replicative lifespan: increased silencing: increased
Large-scale survey
null	competitive fitness: decreased respiratory growth: decreased rate viable

Interactions	AAT1 All interactions details and references
	10 total interaction(s) for 10 unique genes/features.
Genetic Interactions	Phenotypic Enhancement: 1 Phenotypic Suppression: 9

Sequence Information

ChrXI:237180 to 238535 | |

Last Update

Coordinates: 2005-12-15 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1356	237180..238535	2005-12-15	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001589

AAT1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for AAT1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for AAT1]

1)	Morin PJ, et al. (1992) AAT1, a gene encoding a mitochondrial aspartate aminotransferase in Saccharomyces cerevisiae. Biochim Biophys Acta 1171(2):211-4

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