ARR3/YPR201W Summary

ARR3 BASIC INFORMATION

Standard Name	ARR3 (see Nomenclature conflict Note)
Systematic Name	YPR201W
Alias	ACR3 1
Feature Type	ORF, Verified
Description	Arsenite transporter of the plasma membrane, required for resistance to arsenic compounds; transcription is activated by Arr1p in the presence of arsenite (2)
Name Description	ARsenicals Resistance

GO Annotations	All ARR3 GO evidence and references
	View Computational GO annotations for ARR3
Molecular Function
Manually curated	antimonite transmembrane transporter activity (IMP) arsenite transmembrane transporter activity (IGI, ISS)
Biological Process
Manually curated	antimonite transport (IMP) arsenite transport (IGI)
Cellular Component
Manually curated	plasma membrane (IDA)

Mutant Phenotype	All ARR3 Phenotype details and references
Classical genetics
null	cell cycle progression in G1 phase: delayed arsenic accumulation: increased resistance to sodium arsenate: decreased resistance to antimonite: decreased resistance to arsenite(3-): decreased
overexpression	resistance to sodium metaarsenite: increased resistance to sodium arsenate: normal resistance to antimonite: increased resistance to arsenite(3-): increased
Large-scale survey
null	competitive fitness: decreased hyperosmotic stress resistance: decreased viable

Interactions	ARR3 All interactions details and references
	View additional details at BioGRID
	24 total interaction(s) for 19 unique genes/features.
Physical Interactions	PCA: 10 Two-hybrid: 2
Genetic Interactions	Dosage Rescue: 2 Negative Genetic: 2 Phenotypic Enhancement: 4 Positive Genetic: 1 Synthetic Growth Defect: 3

Sequence Information

ChrXVI:939918 to 941132 | |

Last Update

Coordinates: 2004-07-21 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1215	939918..941132	2004-07-21	1996-07-31

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| TCDB \| UniProtKB

Primary SGDID	S000006405

ARR3 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for ARR3

NOMENCLATURE CONFLICT NOTE

Name	Relevance	Description
ACR3	Nomenclature conflict	"ACR3" is both an alias for YPR201W/ARR3 (an arsenite transporter) and the standard name for ACR3, an unmapped gene involved in aculeacin A sensitivity.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ARR3]

1)	Bobrowicz P, et al. (1997) Isolation of three contiguous genes, ACR1, ACR2 and ACR3, involved in resistance to arsenic compounds in the yeast Saccharomyces cerevisiae. Yeast 13(9):819-28
2)	Wysocki R, et al. (1997) The Saccharomyces cerevisiae ACR3 gene encodes a putative membrane protein involved in arsenite transport. J Biol Chem 272(48):30061-6

SGD^tm pages Database Copyright © 1997-2010 The Board of Trustees of Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. The SGD project at Stanford University is supported by a Genome Research Resource Grant from the US National Human Genome Research Institute, part of the US National Institutes of Health.