POP1/YNL221C Summary Help

POP1 BASIC INFORMATION

Standard Name POP1 1
Systematic Name YNL221C
Feature Type ORF, Verified
Description Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in RNase P (1, 2, 3, 4)
Name Description Processing Of Precursor RNAs 1
GO Annotations All POP1 GO evidence and references
    View Computational GO annotations for POP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All POP1 Phenotype details and references
Classical genetics
conditional
null
Large-scale survey
null
reduction of function
Interactions POP1 All interactions details and references
  View additional details at BioGRID
61 total interaction(s) for 23 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 24
  • Affinity Capture-Western: 18
  • Two-hybrid: 9
Genetic Interactions
  • Negative Genetic: 7
  • Synthetic Lethality: 3
Sequence Information
ChrXIV:233696 to 231069 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2628 233696..231069 2005-11-07 1996-07-31
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005165

POP1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for POP1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for POP1]

1) Lygerou Z, et al.  (1994) The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteins. Genes Dev 8(12):1423-33
2) Chamberlain JR, et al.  (1998) Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP. Genes Dev 12(11):1678-90
3)   personal communication
4) Houser-Scott F, et al.  (2002) Interactions among the protein and RNA subunits of Saccharomyces cerevisiae nuclear RNase P. Proc Natl Acad Sci U S A 99(5):2684-9