CAC2/YML102W Summary Help

CAC2 BASIC INFORMATION

Standard Name CAC2 1
Systematic Name YML102W
Feature Type ORF, Verified
Description Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans (1, 2, 3)
Name Description Chromatin Assembly Complex 1
GO Annotations All CAC2 GO evidence and references
    View Computational GO annotations for CAC2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All CAC2 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions CAC2 All interactions details and references
  View additional details at BioGRID
192 total interaction(s) for 112 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 9
  • Affinity Capture-Western: 10
  • Two-hybrid: 10
Genetic Interactions
  • Negative Genetic: 88
  • Phenotypic Enhancement: 19
  • Phenotypic Suppression: 1
  • Positive Genetic: 21
  • Synthetic Growth Defect: 29
  • Synthetic Lethality: 4
  • Synthetic Rescue: 1
Sequence Information
ChrXIII:68294 to 69700 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1407 68294..69700 1996-07-31 1996-07-31
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004570

CAC2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for CAC2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CAC2]

1) Kaufman PD, et al.  (1997) Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I. Genes Dev 11(3):345-57
2) Enomoto S and Berman J  (1998) Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci. Genes Dev 12(2):219-32
3) Krude T  (2002) Chromatin assembly: the kinetochore connection. Curr Biol 12(7):R256-8