ASP3-4/YLR160C Summary Help

ASP3-4 BASIC INFORMATION

Standard Name ASP3-4
Systematic Name YLR160C
Alias ASP3
Feature Type ORF, Verified
Description Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C (1, 2 and see Summary Paragraph)
Name Description ASParaginase
GO Annotations All ASP3-4 GO evidence and references
    View Computational GO annotations for ASP3-4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Pathways
Mutant Phenotype All ASP3-4 Phenotype details and references
Large-scale survey
overexpression
Interactions ASP3-4 All interactions details and references
3 total interaction(s) for 3 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • PCA: 1
Genetic Interactions
  • Phenotypic Suppression: 1
Sequence Information
ChrXII:487290 to 486202 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1089 487290..486202 1996-07-31 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004150

ASP3-4 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for ASP3-4

REPEATED NOTE

NameRelevanceDescription
ASP3-1RepeatedThere are 4 copies of ASP3 in the genome.
ASP3-2RepeatedThere are 4 copies of ASP3 in the genome.
ASP3-3RepeatedThere are 4 copies of ASP3 in the genome.

SUMMARY PARAGRAPH for ASP3-4

ASP3 encodes a nitrogen catabolite-regulated cell wall L-asparaginase II (1). It is one of two asparaginases in yeast, the other being the constitutive intracellular asparaginase I Asp1p, with which Asp3p shares 46% identity (3). Asp3p catalyzes the conversion of L-asparagine to aspartate and ammonia. Asp3p is secreted in response to nitrogen starvation and appears to be regulated by Gln3p/Ure2p (4). ASP3 is located at the junction on chromosome XII with the rRNA genes and is repeated at least four times, to create ASP3-1, ASP3-2, ASP3-3, ASP3-4.

Last updated: 1999-09-01

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ASP3-4]

1) Kim KW, et al.  (1988) Asparaginase II of Saccharomyces cerevisiae. Characterization of the ASP3 gene. J Biol Chem 263(24):11948-53
2) Oliveira EM, et al.  (2003) The role of the GATA factors Gln3p, Nil1p, Dal80p and the Ure2p on ASP3 regulation in Saccharomyces cerevisiae. Yeast 20(1):31-7
3) Sinclair K, et al.  (1994) The ASP1 gene of Saccharomyces cerevisiae, encoding the intracellular isozyme of L-asparaginase. Gene 144(1):37-43
4) Bon EP, et al.  (1997) Asparaginase II of Saccharomyces cerevisiae. GLN3/URE2 regulation of a periplasmic enzyme. Appl Biochem Biotechnol 63-65():203-12