GTT2/YLL060C Summary

GTT2 BASIC INFORMATION

Standard Name	GTT2 1
Systematic Name	YLL060C
Feature Type	ORF, Verified
Description	Glutathione S-transferase capable of homodimerization; functional overlap with Gtt2p, Grx1p, and Grx2p (1, 2)
Name Description	GlutaThione Transferase 1

GO Annotations	All GTT2 GO evidence and references
	View Computational GO annotations for GTT2
Molecular Function
Manually curated	glutathione transferase activity (IDA, ISS)
Biological Process
Manually curated	glutathione metabolic process (IDA)
Cellular Component
High-throughput	mitochondrion (IDA)

Pathways	glutathione-glutaredoxin redox reactions

Mutant Phenotype	All GTT2 Phenotype details and references
Classical genetics
null	resistance to diethylmaleate: decreased resistance to diamide: decreased resistance to tert-butyl hydroperoxide: decreased
Large-scale survey
null	competitive fitness: decreased viable

Interactions	GTT2 All interactions details and references
	14 total interaction(s) for 13 unique genes/features.
Physical Interactions	Affinity Capture-MS: 10 Affinity Capture-RNA: 1 Two-hybrid: 3

Sequence Information

ChrXII:21839 to 21138 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..702	21839..21138	1996-07-31	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003983

GTT2 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for GTT2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GTT2]

1)	Choi JH, et al. (1998) A novel membrane-bound glutathione S-transferase functions in the stationary phase of the yeast Saccharomyces cerevisiae. J Biol Chem 273(45):29915-22
2)	Collinson EJ and Grant CM (2003) Role of yeast glutaredoxins as glutathione S-transferases. J Biol Chem 278(25):22492-7

SGD^tm pages Database Copyright © 1997-2010 The Board of Trustees of Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. The SGD project at Stanford University is supported by a Genome Research Resource Grant from the US National Human Genome Research Institute, part of the US National Institutes of Health.