CBT1/YKL208W Summary Help

CBT1 BASIC INFORMATION

Standard Name CBT1
Systematic Name YKL208W
Alias SOC1 1
Feature Type ORF, Verified
Description Protein involved in 5' end processing of mitochondrial COB, 15S_rRNA, and RPM1 transcripts; may also have a role in 3' end processing of the COB pre-mRNA; displays genetic interaction with cell cycle-regulated kinase Dbf2p (1, 2, 3)
Name Description Cytochrome B Termination 3
GO Annotations All CBT1 GO evidence and references
    View Computational GO annotations for CBT1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Mutant Phenotype All CBT1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions CBT1 All interactions details and references
  View additional details at BioGRID
108 total interaction(s) for 107 unique genes/features.
Genetic Interactions
  • Negative Genetic: 84
  • Positive Genetic: 23
  • Synthetic Rescue: 1

Sequence Information
ChrXI:47158 to 47973 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..816 47158..47973 1996-07-31 1996-07-31
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001691

CBT1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CBT1]

1) Ellis TP, et al.  (2005) CBT1 interacts genetically with CBP1 and the mitochondrially encoded cytochrome b gene and is required to stabilize the mature cytochrome b mRNA of Saccharomyces cerevisiae. Genetics 171(3):949-57
2) Grandin N and Charbonneau M  (1999) Dbf2 is implicated in a Cbt1-dependent pathway following a shift from glucose to galactose or non-fermentable carbon sources in Saccharomyces cerevisiae. Mol Gen Genet 261(2):402-7
3) Rieger KJ, et al.  (1997) A novel nuclear gene, CBT1, essential for mitochondrial cytochrome b formation: terminal processing of mRNA and intron dependence. Curr Genet 32(3):163-74