DBR1/YKL149C Summary

DBR1 BASIC INFORMATION

Standard Name	DBR1 1
Systematic Name	YKL149C
Alias	PRP26 2
Feature Type	ORF, Verified
Description	RNA lariat debranching enzyme, involved in intron turnover; required for efficient Ty1 transposition (1)
Name Description	DeBRanching 1

GO Annotations	All DBR1 GO evidence and references
	View Computational GO annotations for DBR1
Molecular Function
Manually curated	RNA lariat debranching enzyme activity (IDA, IMP)
Biological Process
Manually curated	pseudohyphal growth (IMP) RNA catabolic process (IDA, IMP) snoRNA metabolic process (IMP) transposition, RNA-mediated (IMP)
Cellular Component
Manually curated	nucleus (IC)

Mutant Phenotype	All DBR1 Phenotype details and references
Classical genetics
unspecified	pseudohyphal growth: decreased
Large-scale survey
null	transposable element transposition: decreased viable

Interactions	DBR1 All interactions details and references
	44 total interaction(s) for 38 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Biochemical Activity: 1
Genetic Interactions	Phenotypic Enhancement: 20 Phenotypic Suppression: 21 Synthetic Lethality: 1

Sequence Information

ChrXI:168834 to 167617 | |

Note: this feature is encoded on the Crick strand.

Genetic position: -106.4 cM

Last Update

Coordinates: 2004-02-13 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1218	168834..167617	2004-02-13	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001632

DBR1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for DBR1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for DBR1]

1)	Chapman KB and Boeke JD (1991) Isolation and characterization of the gene encoding yeast debranching enzyme. Cell 65(3):483-92
2)	Vijayraghavan U, et al. (1989) Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev 3(8):1206-16

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