MAE1/YKL029C Summary

MAE1 BASIC INFORMATION

Standard Name	MAE1
Systematic Name	YKL029C
Feature Type	ORF, Verified
Description	Mitochondrial malic enzyme, catalyzes the oxidative decarboxylation of malate to pyruvate, which is a key intermediate in sugar metabolism and a precursor for synthesis of several amino acids (1)
Name Description	MAlic Enzyme 1

GO Annotations	All MAE1 GO evidence and references
	View Computational GO annotations for MAE1
Molecular Function
Manually curated	malic enzyme activity (IDA, ISS)
Biological Process
Manually curated	cellular amino acid metabolic process (IMP) pyruvate metabolic process (IMP)
Cellular Component
Manually curated	mitochondrion (IDA)
High-throughput	mitochondrion (IDA)

Pathways	gluconeogenesis

Mutant Phenotype	All MAE1 Phenotype details and references
Classical genetics
null	viable
Large-scale survey
null	competitive fitness: increased viable

Interactions	MAE1 All interactions details and references
	View additional details at BioGRID
	95 total interaction(s) for 80 unique genes/features.
Physical Interactions	Affinity Capture-MS: 61
Genetic Interactions	Negative Genetic: 32 Synthetic Growth Defect: 1 Synthetic Rescue: 1

Sequence Information

ChrXI:384368 to 382359 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2005-12-15 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..2010	384368..382359	2005-12-15	1996-07-31

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001512

MAE1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for MAE1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for MAE1]

1)	Boles E, et al. (1998) Identification and characterization of MAE1, the Saccharomyces cerevisiae structural gene encoding mitochondrial malic enzyme. J Bacteriol 180(11):2875-82

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