MNN11/YJL183W Summary

MNN11 BASIC INFORMATION

Standard Name	MNN11
Systematic Name	YJL183W
Feature Type	ORF, Verified
Description	Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p (1)
Name Description	MaNNosyltransferase

GO Annotations	All MNN11 GO evidence and references
	View Computational GO annotations for MNN11
Molecular Function
Manually curated	alpha-1,6-mannosyltransferase activity (IDA)
Biological Process
Manually curated	protein amino acid glycosylation (IDA, IMP)
Cellular Component
Manually curated	alpha-1,6-mannosyltransferase complex (IPI)

Mutant Phenotype	All MNN11 Phenotype details and references
Classical genetics
null	sterol ester accumulation: increased protein secretion: increased resistance to Calcofluor White: decreased
Large-scale survey
null	glutathione excretion: increased chitin deposition: increased competitive fitness: decreased freeze-thaw resistance: decreased heat sensitivity: increased metal resistance: decreased Can1p-GFP distribution: abnormal Fus-Mid-GFP distribution: abnormal resistance to Calcofluor White: decreased resistance to doxorubicin: decreased resistance to ethanol: decreased resistance to methanol: decreased resistance to propan-1-ol: decreased resistance to 1,4-dithiothreitol: decreased resistance to rapamycin: decreased resistance to sulfometuron methyl: decreased toxin resistance: decreased viable

Interactions	MNN11 All interactions details and references
	View additional details at BioGRID
	458 total interaction(s) for 325 unique genes/features.
Physical Interactions	Affinity Capture-MS: 18 Affinity Capture-Western: 11 Co-purification: 1 PCA: 1 Two-hybrid: 6
Genetic Interactions	Negative Genetic: 324 Positive Genetic: 60 Synthetic Growth Defect: 14 Synthetic Lethality: 23

Sequence Information

ChrX:84066 to 85334 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1269	84066..85334	1996-07-31	1996-07-31

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003719

MNN11 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for MNN11

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for MNN11]

1)	Jungmann J, et al. (1999) The Saccharomyces cerevisiae protein Mnn10p/Bed1p is a subunit of a Golgi mannosyltransferase complex. J Biol Chem 274(10):6579-85

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