AIM22/YJL046W Summary Help

AIM22 BASIC INFORMATION

Standard Name AIM22 1
Systematic Name YJL046W
Alias LIP3 2 , RRG3 3
Feature Type ORF, Verified
Description Putative lipoate-protein ligase, required along with Lip2 and Lip5 for lipoylation of Lat1p and Kgd2p; similar to E. coli LplA; null mutant displays reduced frequency of mitochondrial genome loss (1, 2, 4, 5, 6)
Name Description Altered Inheritance rate of Mitochondria 1
GO Annotations All AIM22 GO evidence and references
    View Computational GO annotations for AIM22
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All AIM22 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions AIM22 All interactions details and references
  View additional details at BioGRID
128 total interaction(s) for 92 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
Genetic Interactions
  • Negative Genetic: 115
  • Positive Genetic: 5
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 4
Sequence Information
ChrX:352380 to 353609 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2009-02-18 | Sequence: 2005-12-01
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1230 352380..353609 2009-02-18 2005-12-01
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003582

AIM22 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for AIM22

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for AIM22]

1) Hess DC, et al.  (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407
2) Schonauer MS, et al.  (2009) Lipoic Acid synthesis and attachment in yeast mitochondria. J Biol Chem 284(35):23234-42
3) Merz S and Westermann B  (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
4) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
5) Steinmetz LM, et al.  (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
6) Tatusov RL, et al.  (1997) A genomic perspective on protein families. Science 278(5338):631-7