INM1/YHR046C Summary

INM1 BASIC INFORMATION

Standard Name	INM1 1
Systematic Name	YHR046C
Feature Type	ORF, Verified
Description	Inositol monophosphatase, involved in biosynthesis of inositol and in phosphoinositide second messenger signaling; INM1 expression increases in the presence of inositol and decreases upon exposure to antibipolar drugs lithium and valproate (1)
Name Description	INositol Monophosphatase 1

GO Annotations	All INM1 GO evidence and references
	View Computational GO annotations for INM1
Molecular Function
Manually curated	inositol-1(or 4)-monophosphatase activity (IDA, ISS)
Biological Process
Manually curated	inositol phosphate dephosphorylation (IDA)
Cellular Component
High-throughput	cytoplasm (IDA) nucleus (IDA)

Pathways	myo-inositol biosynthesis

Mutant Phenotype	All INM1 Phenotype details and references
Large-scale survey
null	replicative lifespan: increased viable

Interactions	INM1 All interactions details and references
	13 total interaction(s) for 13 unique genes/features.
Physical Interactions	Affinity Capture-MS: 3
Genetic Interactions	Phenotypic Enhancement: 2 Phenotypic Suppression: 5 Synthetic Growth Defect: 2 Synthetic Lethality: 1

Sequence Information

ChrVIII:198278 to 197391 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2005-11-07 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..888	198278..197391	2005-11-07	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001088

INM1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for INM1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for INM1]

1)	Murray M and Greenberg ML (2000) Expression of yeast INM1 encoding inositol monophosphatase is regulated by inositol, carbon source and growth stage and is decreased by lithium and valproate. Mol Microbiol 36(3):651-61

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