COS8/YHL048W Summary Help

COS8 BASIC INFORMATION

Standard Name COS8
Systematic Name YHL048W
Feature Type ORF, Verified
Description Nuclear membrane protein, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; regulation suggests a potential role in the unfolded protein response (1, 2)
Name Description COnserved Sequence
GO Annotations All COS8 GO evidence and references
    View Computational GO annotations for COS8
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All COS8 Phenotype details and references
Classical genetics
null
Interactions COS8 All interactions details and references
  View additional details at BioGRID
48 total interaction(s) for 48 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • PCA: 46
  • Two-hybrid: 1
Sequence Information
ChrVIII:6400 to 7545 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1146 6400..7545 1996-07-31 1996-07-31
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001040

COS8 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for COS8

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for COS8]

1) Spode I, et al.  (2002) ATF/CREB sites present in sub-telomeric regions of Saccharomyces cerevisiae chromosomes are part of promoters and act as UAS/URS of highly conserved COS genes. J Mol Biol 319(2):407-20
2) Despons L, et al.  (2006) An evolutionary scenario for one of the largest yeast gene families. Trends Genet 22(1):10-5