APM2/YHL019C Summary

APM2 BASIC INFORMATION

Standard Name	APM2 1
Systematic Name	YHL019C
Feature Type	ORF, Verified
Description	Protein of unknown function, homologous to the medium chain of mammalian clathrin-associated protein complex; involved in vesicular transport (1)
Name Description	clathrin Adaptor Protein complex Medium chain 1

GO Annotations	All APM2 GO evidence and references
	View Computational GO annotations for APM2
Molecular Function
Manually curated	clathrin binding (ISS)
Biological Process
Manually curated	Golgi to vacuole transport (IMP) vesicle-mediated transport (ISS)
Cellular Component
Manually curated	AP-1 adaptor complex (IPI)

Mutant Phenotype	All APM2 Phenotype details and references
Classical genetics
null	toxin resistance: decreased vacuolar transport: abnormal
Large-scale survey
null	UV resistance: decreased hyperosmotic stress resistance: decreased toxin resistance: decreased viable
overexpression	resistance to rapamycin: decreased

Interactions	APM2 All interactions details and references
	23 total interaction(s) for 10 unique genes/features.
Physical Interactions	Affinity Capture-MS: 13 Affinity Capture-Western: 2 Biochemical Activity: 4 Two-hybrid: 2
Genetic Interactions	Dosage Rescue: 2

Sequence Information

ChrVIII:69545 to 67728 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2005-11-07 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1818	69545..67728	2005-11-07	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001011

APM2 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for APM2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for APM2]

1)	Stepp JD, et al. (1995) A late Golgi sorting function for Saccharomyces cerevisiae Apm1p, but not for Apm2p, a second yeast clathrin AP medium chain-related protein. Mol Biol Cell 6(1):41-58

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