SDT1/YGL224C Summary

SDT1 BASIC INFORMATION

Standard Name	SDT1
Systematic Name	YGL224C
Alias	SSM1
Feature Type	ORF, Verified
Description	Pyrimidine nucleotidase; overexpression suppresses the 6-AU sensitivity of transcription elongation factor S-II, as well as resistance to other pyrimidine derivatives (1)
Name Description	Suppressor of Disruption of TFIIS 2

GO Annotations	All SDT1 GO evidence and references
	View Computational GO annotations for SDT1
Molecular Function
Manually curated	nucleotidase activity (IDA)
Biological Process
Manually curated	pyrimidine base metabolic process (IMP)
Cellular Component
Manually curated	cellular_component unknown (ND)

Mutant Phenotype	All SDT1 Phenotype details and references
Large-scale survey
null	UV resistance: decreased toxin resistance: decreased viable

Interactions	SDT1 All interactions details and references
	3 total interaction(s) for 3 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 1
Genetic Interactions	Dosage Rescue: 1

Sequence Information

ChrVII:78856 to 78014 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-07-15 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..843	78856..78014	2004-07-15	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003192

SDT1 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for SDT1

NOMENCLATURE CONFLICT NOTE

Name	Relevance	Description
RPL1A	Nomenclature conflict	SSM1 has been used to refer to both SDT1/YGL224C, a nucleotidase, and RPL1A/YPL220W, a ribosomal protein.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SDT1]

1)	Nakanishi T and Sekimizu K (2002) SDT1/SSM1, a multicopy suppressor of S-II null mutant, encodes a novel pyrimidine 5'-nucleotidase. J Biol Chem 277(24):22103-6
2)	Uptain SM, et al. (1997) Basic mechanisms of transcript elongation and its regulation. Annu Rev Biochem 66:117-72

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