HPA3/YEL066W Summary

HPA3 BASIC INFORMATION

Standard Name	HPA3
Systematic Name	YEL066W
Feature Type	ORF, Verified
Description	D-Amino acid N-acetyltransferase, catalyzes N-acetylation of D-amino acids through ordered bi-bi mechanism in which acetyl-CoA is first substrate bound and CoA is last product liberated; similar to Hpa2p, acetylates histones weakly in vitro (1, 2)
Name Description	Histone and other Protein Acetyltransferase

GO Annotations	All HPA3 GO evidence and references
	View Computational GO annotations for HPA3
Molecular Function
Manually curated	D-amino-acid N-acetyltransferase activity (IDA)
Biological Process
Manually curated	D-amino acid metabolic process (IMP)
Cellular Component
High-throughput	cytoplasm (IDA) nucleus (IDA)

Mutant Phenotype	All HPA3 Phenotype details and references
Large-scale survey
null	viable

Interactions	HPA3 All interactions details and references
	10 total interaction(s) for 10 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 Two-hybrid: 4
Genetic Interactions	Synthetic Growth Defect: 4 Synthetic Lethality: 1

Sequence Information

ChrV:26667 to 27206 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..540	26667..27206	1996-07-31	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000792

HPA3 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for HPA3

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for HPA3]

1)	Angus-Hill ML, et al. (1999) Crystal structure of the histone acetyltransferase Hpa2: A tetrameric member of the Gcn5-related N-acetyltransferase superfamily. J Mol Biol 294(5):1311-25
2)	Yow GY, et al. (2004) D-amino acid N-acetyltransferase of Saccharomyces cerevisiae: a close homologue of histone acetyltransferase Hpa2p acting exclusively on free D-amino acids. Arch Microbiol 182(5):396-403

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