NPP2/YEL016C Summary

NPP2 BASIC INFORMATION

Standard Name	NPP2 1
Systematic Name	YEL016C
Feature Type	ORF, Verified
Description	Nucleotide pyrophosphatase/phosphodiesterase family member; mediates extracellular nucleotide phosphate hydrolysis along with Npp1p and Pho5p; activity and expression enhanced during conditions of phosphate starvation (1)
Name Description	ecto-nucleotide pyrophosphatase/ phosphodiesterase 1

GO Annotations	All NPP2 GO evidence and references
	View Computational GO annotations for NPP2
Molecular Function
Manually curated	nucleoside-triphosphatase activity (IGI, IMP) nucleoside-triphosphate diphosphatase activity (IDA, IGI, IMP) nucleotide diphosphatase activity (ISS) phosphodiesterase I activity (ISS)
Biological Process
Manually curated	nucleoside triphosphate metabolic process (IMP)
Cellular Component
Manually curated	cellular_component unknown (ND)

Mutant Phenotype	All NPP2 Phenotype details and references
Classical genetics
null	hyperosmotic stress resistance: increased viable
Large-scale survey
null	sporulation: normal viable
overexpression	vegetative growth: decreased

Interactions	NPP2 All interactions details and references
	3 total interaction(s) for 3 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1
Genetic Interactions	Phenotypic Enhancement: 1 Phenotypic Suppression: 1

Sequence Information

ChrV:126218 to 124737 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1482	126218..124737	1996-07-31	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000742

NPP2 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for NPP2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NPP2]

1)	Kennedy EJ, et al. (2005) Pho5p and newly identified nucleotide pyrophosphatases/ phosphodiesterases regulate extracellular nucleotide phosphate metabolism in Saccharomyces cerevisiae. Eukaryot Cell 4(11):1892-901

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