INM2/YDR287W Summary Help

INM2 BASIC INFORMATION

Standard Name INM2 (see Nomenclature conflict Note)
Systematic Name YDR287W
Feature Type ORF, Verified
Description Inositol monophosphatase, involved in biosynthesis of inositol; enzymatic activity requires magnesium ions and is inhibited by lithium and sodium ions; inm1 inm2 double mutant lacks inositol auxotrophy (1)
Name Description INositol Monophosphatase 2
GO Annotations All INM2 GO evidence and references
    View Computational GO annotations for INM2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Pathways
Mutant Phenotype All INM2 Phenotype details and references
Classical genetics
overexpression
Large-scale survey
null
Interactions INM2 All interactions details and references
  View additional details at BioGRID
21 total interaction(s) for 17 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
Genetic Interactions
  • Negative Genetic: 15
  • Positive Genetic: 3
  • Synthetic Lethality: 1
Sequence Information
ChrIV:1035992 to 1036870 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2008-06-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..879 1035992..1036870 2008-06-05 1996-07-31
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002695

INM2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for INM2

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
IMP2'Nomenclature conflictThe gene name IMP2 has been used to refer to the transcriptional coactivator IMP2'/YIL154C, the inositol monophosphatase INM2/YDR287W, and the mitochondrial inner membrane peptidase IMP2/YMR035W.
IMP2Nomenclature conflictThe gene name IMP2 has been used to refer to the transcriptional coactivator IMP2'/YIL154C, the inositol monophosphatase INM2/YDR287W, and the mitochondrial inner membrane peptidase IMP2/YMR035W.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for INM2]

1) Lopez F, et al.  (1999) The yeast inositol monophosphatase is a lithium- and sodium-sensitive enzyme encoded by a non-essential gene pair. Mol Microbiol 31(4):1255-64
2) Murray M and Greenberg ML  (2000) Expression of yeast INM1 encoding inositol monophosphatase is regulated by inositol, carbon source and growth stage and is decreased by lithium and valproate. Mol Microbiol 36(3):651-61