CHA1/YCL064C Summary

CHA1 BASIC INFORMATION

Standard Name	CHA1 1
Systematic Name	YCL064C
Feature Type	ORF, Verified
Description	Catabolic L-serine (L-threonine) deaminase, catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine (1, 2)
Name Description	Catabolism of Hydroxy Amino acids 1

GO Annotations	All CHA1 GO evidence and references
	View Computational GO annotations for CHA1
Molecular Function
Manually curated	L-serine ammonia-lyase activity (IDA) L-threonine ammonia-lyase activity (IDA)
Biological Process
Manually curated	L-serine catabolic process (IGI) threonine catabolic process (IGI)
Cellular Component
Manually curated	mitochondrial nucleoid (IDA)
High-throughput	mitochondrion (IDA)

Pathways	L-serine degradation threonine catabolism

Mutant Phenotype	All CHA1 Phenotype details and references
Classical genetics
null	utilization of nitrogen source: decreased
Large-scale survey
null	viable

Interactions	CHA1 All interactions details and references
	2 total interaction(s) for 2 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1
Genetic Interactions	Dosage Rescue: 1

Sequence Information

ChrIII:16880 to 15798 | |

Note: this feature is encoded on the Crick strand.

Genetic position: -46 cM

Last Update

Coordinates: 2000-09-13 | Sequence: 2000-09-13

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1083	16880..15798	2000-09-13	2000-09-13

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000569

CHA1 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for CHA1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CHA1]

1)	Petersen JG, et al. (1988) Molecular genetics of serine and threonine catabolism in Saccharomyces cerevisiae. Genetics 119(3):527-34
2)	Bornaes C, et al. (1993) A regulatory element in the CHA1 promoter which confers inducibility by serine and threonine on Saccharomyces cerevisiae genes. Mol Cell Biol 13(12):7604-11

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