YBL055C Summary

YBL055C BASIC INFORMATION

Systematic Name	YBL055C
Feature Type	ORF, Verified
Description	3'-->5' exonuclease and endonuclease with a possible role in apoptosis; has similarity to mammalian and C. elegans apoptotic nucleases (1) Also known as: Tat-D 1

GO Annotations	All YBL055C GO evidence and references
	View Computational GO annotations for YBL055C
Molecular Function
Manually curated	3'-5'-exodeoxyribonuclease activity (IDA) endonuclease activity (IDA)
Biological Process
Manually curated	cellular response to oxidative stress (IMP) DNA fragmentation involved in apoptotic nuclear change (IMP)
Cellular Component
High-throughput	cytoplasm (IDA)

Mutant Phenotype	All YBL055C Phenotype details and references
Classical genetics
null	chromosome/plasmid maintenance: abnormal oxidative stress resistance: increased viable
overexpression	oxidative stress resistance: decreased
Large-scale survey
null	competitive fitness: increased filamentous growth: increased invasive growth: absent viable

Interactions	YBL055C All interactions details and references
	View additional details at BioGRID
	17 total interaction(s) for 17 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Biochemical Activity: 8
Genetic Interactions	Negative Genetic: 6 Synthetic Growth Defect: 1

Sequence Information

ChrII:116832 to 115576 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-07-16 | Sequence: 1997-01-28

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1257	116832..115576	2004-07-16	1997-01-28

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000151

YBL055C RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for YBL055C

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for YBL055C]

1)	Qiu J, et al. (2005) Search for apoptotic nucleases in yeast: role of Tat-D nuclease in apoptotic DNA degradation. J Biol Chem 280(15):15370-9

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