ACH1/YBL015W Summary Help

ACH1 BASIC INFORMATION

Standard Name ACH1 1
Systematic Name YBL015W
Feature Type ORF, Verified
Description Protein with CoA transferase activity, particularly for CoASH transfer from succinyl-CoA to acetate; has minor acetyl-CoA-hydrolase activity; phosphorylated; required for acetate utilization and for diploid pseudohyphal growth (2, 3, 4)
Name Description Acetyl CoA Hydrolase 1
GO Annotations All ACH1 GO evidence and references
    View Computational GO annotations for ACH1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All ACH1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions ACH1 All interactions details and references
7 total interaction(s) for 7 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Co-purification: 1

Genetic Interactions
  • Synthetic Lethality: 1

Sequence Information
ChrII:194125 to 195705 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1581 194125..195705 2004-07-16 1997-01-28
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000111

ACH1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ACH1]

1) Lee FJ, et al.  (1990) A glucose-repressible gene encodes acetyl-CoA hydrolase from Saccharomyces cerevisiae. J Biol Chem 265(13):7413-8
2) Buu LM, et al.  (2003) Functional characterization and localization of acetyl-CoA hydrolase, Ach1p, in Saccharomyces cerevisiae. J Biol Chem 278(19):17203-9
3) Reinders J, et al.  (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906
4) Fleck CB and Brock M  (2009) Re-characterisation of Saccharomyces cerevisiae Ach1p: fungal CoA-transferases are involved in acetic acid detoxification. Fungal Genet Biol 46(6-7):473-85